Screens regions with strong signals without using LD.

screen_regions_noLD(
  region_data,
  group_prior = NULL,
  group_prior_var = NULL,
  min_var = 2,
  min_gene = 1,
  min_nonSNP_PIP = 0.5,
  ncore = 1,
  logfile = NULL,
  verbose = FALSE,
  ...
)

Arguments

region_data

a list object indexing regions, variants and genes.

group_prior

a vector of two prior inclusion probabilities for SNPs and genes.

group_prior_var

a vector of two prior variances for SNPs and gene effects.

min_var

minimum number of variables (SNPs and genes) in a region.

min_gene

minimum number of genes in a region.

min_nonSNP_PIP

If screening by non-SNP PIPs, regions with total non-SNP PIP >= min_nonSNP_PIP will be selected to run finemapping using full SNPs.

ncore

The number of cores used to parallelize susie over regions.

logfile

The log filename. If NULL, print log info on screen.

verbose

If TRUE, print detail messages.

...

Additional arguments of susie_rss.

Value

a list, containing a data frame of selected region data, and a data frame of screening summary for all regions.