Runs cTWAS fine-mapping for regions without LD (L = 1)

finemap_regions_noLD(
  region_data,
  group_prior = NULL,
  group_prior_var = NULL,
  use_null_weight = TRUE,
  get_susie_alpha = TRUE,
  snps_only = FALSE,
  ncore = 1,
  verbose = FALSE,
  logfile = NULL,
  ...
)

Arguments

region_data

region_data to be finemapped

group_prior

a vector of two prior inclusion probabilities for SNPs and genes. If NULL, it will use uniform prior inclusion probabilities.

group_prior_var

a vector of two prior variances for SNPs and gene effects. If NULL, it will set prior variance = 50 as the default in susie_rss.

use_null_weight

If TRUE, allow for a probability of no effect in susie

get_susie_alpha

If TRUE, get susie alpha matrix from finemapping results.

snps_only

If TRUE, use only SNPs in the region data.

ncore

The number of cores used to parallelize computation over regions

verbose

If TRUE, print detail messages

logfile

the log file, if NULL will print log info on screen

...

Additional arguments of susie_rss.

Value

a data frame of cTWAS finemapping results.