Last updated: 2025-12-08
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Knit directory: Lung_scMultiomics_paper/
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Previous study showed immune cells have a shared role in the development of both AOA and COA based on heritability analysis on ATAC-seq data of blood and lung cell types. Due to lack of resolution, it is unclear if different immune subsets sampled from lung or other tissues can have distinct roles in the genetics of asthma.
Single-cell multiomics on paired lung and spleen samples from 9 donors (6 controls and 3 cases).