All functions | 
      |
|---|---|
annotate susie results. this will generate output text files  | 
      |
Extract regression coefficients from susie fit  | 
      |
Compute sufficient statistics for susie.  | 
      |
Converts PLINK genotype data to LD matrices and SNP info files, saves LD matrices as .RDS files and SNP info as .Rvar files  | 
      |
Causal inference for TWAS  | 
      |
Plot the output of cTWAS at a single locus  | 
      |
Create the gene track for the cTWAS locus plot  | 
      |
Causal inference for TWAS using summary statistics  | 
      |
Summarize and plot cTWAS parameter estimates  | 
      |
filter regions based on probality of at most 1 causal effect  | 
      |
Harmonize z scores from GWAS to match ld reference genotypes. Flip signs when reverse complement matches, remove/recover strand ambiguous SNPs  | 
      |
Harmonize z scores from GWAS to match ld reference genotypes. Flip signs when reverse complement matches.  | 
      |
Impute expression  | 
      |
Impute expression z scores  | 
      |
Get gene and SNP index for each region  | 
      |
Predict outcomes or extract coefficients from susie fit.  | 
      |
Harmonize GWAS summary statistics and LD reference  | 
      |
Prepare .exprvar file  | 
      |
Read .pgen file into R  | 
      |
Prepare .pvar file  | 
      |
Read .bim file into R  | 
      |
Read .expr file into R  | 
      |
Read .exprvar file into R  | 
      |
read variant information for all ld matrices in `ld_Rf`.  | 
      |
read variant information associated with a LD R matrix .RDS file.  | 
      |
Read pgen file into R  | 
      |
Read .pvar file into R  | 
      |
Read variant information from .pvar or .bim file into R  | 
      |
parallel regions  | 
      |
Sum of Single Effects (SuSiE) Regression  | 
      |
Iteratively run susie and estimate parameters  | 
      |
Iteratively run susie and estimate parameters - RSS version  | 
      |
| 
           
  | 
        Inferences From Fitted SuSiE Model  | 
      
Initialize a susie object using regression coefficients  | 
      |
Sum of Single Effects (SuSiE) Regression using summary statistics  | 
      |
Perform Univariate Linear Regression Separately for Columns of X  | 
      |
combine variant information associated with a LD R matrix .RDS file.  | 
      |